The Multiple Layers of the Tumor Environment - HAL-SHS - Sciences de l'Homme et de la Société Accéder directement au contenu
Article Dans Une Revue Trends in Cancer Année : 2018

The Multiple Layers of the Tumor Environment

Résumé

The notion of tumor microenvironment (TME) has been brought to the forefront of recent scientific literature on cancer. However, there is no consensus on how to define and spatially delineate the TME. We propose that the time is ripe to go beyond an all-encompassing list of the components of the TME, and to construct a multilayered view of cancer. We distinguish six layers of environmental interactions with the tumor and show that they are associated with distinct mechanisms, and ultimately with distinct therapeutic approaches.
Fichier principal
Vignette du fichier
Laplane-Duluc-Larmonier-Pradeu-Bikfalvi_The Multiple Layers of the Tumor Environment_Final draft.pdf (232.07 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-01964545 , version 1 (22-12-2018)

Identifiants

Citer

Lucie Laplane, Dorothee Duluc, Nicolas Larmonier, Thomas Pradeu, Andreas Bikfalvi. The Multiple Layers of the Tumor Environment. Trends in Cancer, 2018, 4 (12), pp.802-809. ⟨10.1016/j.trecan.2018.10.002⟩. ⟨hal-01964545⟩
156 Consultations
253 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More