Affect intensity measure in bipolar disorders: A multidimensional approach
F. Mathieu
(1)
,
B. Etain
(2)
,
C. Daban
(2)
,
R. Raymond
(2)
,
A. Raust
(2)
,
B. Cochet
(3, 4)
,
S. Gard
(5, 6, 7)
,
K. M'Bailara
(5, 6, 7)
,
A. Desage
(5, 6, 7)
,
J.P. Kahn
(5, 8)
,
O. Wajsbrot-Elgrabli
(5, 8)
,
R.F. Cohen
(5, 8)
,
J.M. Azorin
(5, 9)
,
M. Leboyer
(2, 10)
,
F. Bellivier
(2, 11)
,
J. Scott
(12)
,
C. Henry
(2, 10)
1
DIAGEMM -
Génétique du diabète
2 Inserm U955 - Molecular virology and immunology – Physiopathology and therapeutic of chronic viral hepatitis (Team 18)
3 Pôle de Psychiatrie [Hôpital Henri Mondor]
4 Centre hospitalier Charles Perrens [Bordeaux]
5 Fondation FondaMental [Créteil]
6 Laboratoire de psychologie:Santé et qualité de vie
7 PUP - Pôle Universitaire de Psychiatrie [CHU Bordeaux]
8 Service de Psychiatrie [CHRU Nancy]
9 Hôpitaux Sud - Département Universitaire de Psychiatrie - [Hôpital Sainte Marguerite - APHM]
10 Groupe Henri Mondor-Albert Chenevier
11 HUSLS-LRB-FW - Département de Psychiatrie et de Médecine Addictologique [AP-HP HU Saint-Louis, Lariboisière, Fernand Widal]
12 Newcastle University [Newcastle]
2 Inserm U955 - Molecular virology and immunology – Physiopathology and therapeutic of chronic viral hepatitis (Team 18)
3 Pôle de Psychiatrie [Hôpital Henri Mondor]
4 Centre hospitalier Charles Perrens [Bordeaux]
5 Fondation FondaMental [Créteil]
6 Laboratoire de psychologie:Santé et qualité de vie
7 PUP - Pôle Universitaire de Psychiatrie [CHU Bordeaux]
8 Service de Psychiatrie [CHRU Nancy]
9 Hôpitaux Sud - Département Universitaire de Psychiatrie - [Hôpital Sainte Marguerite - APHM]
10 Groupe Henri Mondor-Albert Chenevier
11 HUSLS-LRB-FW - Département de Psychiatrie et de Médecine Addictologique [AP-HP HU Saint-Louis, Lariboisière, Fernand Widal]
12 Newcastle University [Newcastle]
B. Etain
- Fonction : Auteur
- PersonId : 757741
- IdHAL : bruno-etain
- ORCID : 0000-0002-5377-1488
- IdRef : 074181106
Résumé
Background: Emotional dysregulation, characterized by high levels of both arousal and intensity of emotional responses, is a core feature of bipolar disorders (BDs). In non-clinical populations, the 40-item Affect Intensity Measure (AIM) can be used to assess the different dimensions of emotional reactivity.
Methods: We analyzed the factor structure of the AIM in a sample of 310 euthymic patients with BD using Principal Component Analysis and examined associations between AIM sub-scale scores and demographic and illness characteristics.
Results: The French translation of the AIM demonstrated good reliability. A four-factor solution similar to that reported in non-clinical samples (Positive Affectivity, Unpeacefulness [lack of Serenity], Negative Reactivity, Negative Intensity), explained 47% of the total variance. Age and gender were associated with Unpeacefulness and Negative reactivity respectively. 'Unpeacefulness' was also positively associated with psychotic symptoms at onset (p=0.0006), but negatively associated with co-morbid substance misuse (p=0.008). Negative Intensity was positively associated with social phobia (p=0.0005).
Limitations: We cannot definitively exclude a lack of statistical power to classify all AIM items. Euthymia was carefully defined, but a degree of 'contamination' of the self-reported levels of emotion reactivity may occur because of subsyndromal BD symptoms. It was not feasible to control for the possible impact of on-going treatments.
Conclusions: The AIM scale appears to be a useful measure of emotional reactivity and intensity in a clinical sample of patients with BD, suggesting it can be used in addition to other markers of BD characteristics and sub-types.
Format du dépôt | Notice |
---|---|
Type de dépôt | Article dans une revue |
Résumé |
en
Background: Emotional dysregulation, characterized by high levels of both arousal and intensity of emotional responses, is a core feature of bipolar disorders (BDs). In non-clinical populations, the 40-item Affect Intensity Measure (AIM) can be used to assess the different dimensions of emotional reactivity.
Methods: We analyzed the factor structure of the AIM in a sample of 310 euthymic patients with BD using Principal Component Analysis and examined associations between AIM sub-scale scores and demographic and illness characteristics.
Results: The French translation of the AIM demonstrated good reliability. A four-factor solution similar to that reported in non-clinical samples (Positive Affectivity, Unpeacefulness [lack of Serenity], Negative Reactivity, Negative Intensity), explained 47% of the total variance. Age and gender were associated with Unpeacefulness and Negative reactivity respectively. 'Unpeacefulness' was also positively associated with psychotic symptoms at onset (p=0.0006), but negatively associated with co-morbid substance misuse (p=0.008). Negative Intensity was positively associated with social phobia (p=0.0005).
Limitations: We cannot definitively exclude a lack of statistical power to classify all AIM items. Euthymia was carefully defined, but a degree of 'contamination' of the self-reported levels of emotion reactivity may occur because of subsyndromal BD symptoms. It was not feasible to control for the possible impact of on-going treatments.
Conclusions: The AIM scale appears to be a useful measure of emotional reactivity and intensity in a clinical sample of patients with BD, suggesting it can be used in addition to other markers of BD characteristics and sub-types.
|
Titre |
en
Affect intensity measure in bipolar disorders: A multidimensional approach
|
Auteur(s) |
F. Mathieu
1
, B. Etain
2
, C. Daban
2
, R. Raymond
2
, A. Raust
2
, B. Cochet
3, 4
, S. Gard
5, 6, 7
, K. M'Bailara
5, 6, 7
, A. Desage
5, 6, 7
, J.P. Kahn
5, 8
, O. Wajsbrot-Elgrabli
5, 8
, R.F. Cohen
5, 8
, J.M. Azorin
5, 9
, M. Leboyer
2, 10
, F. Bellivier
2, 11
, J. Scott
12
, C. Henry
2, 10
1
DIAGEMM -
Génétique du diabète
( 485400 )
- Faculté de Médecine Paris Diderot - Site Villemin
10 avenue de Verdun
75010 Paris
- France
2
Inserm U955 -
Molecular virology and immunology – Physiopathology and therapeutic of chronic viral hepatitis (Team 18)
( 569981 )
- Building P – Entresol 1
Hôpital Henri Mondor
51, avenue du Maréchal De Lattre de Tassigny
94010 Créteil - France
- France
3
Pôle de Psychiatrie [Hôpital Henri Mondor]
( 456531 )
- 51 Avenue du Maréchal de Lattre de Tassigny, 94010 Créteil
- France
4
Centre hospitalier Charles Perrens [Bordeaux]
( 300538 )
- France
5
Fondation FondaMental [Créteil]
( 324136 )
- Hôpital Albert Chenevier, Pôle de Psychiatrie, 40 rue de Mesly, 94000 Créteil France
- France
6
Laboratoire de psychologie:Santé et qualité de vie
( 93081 )
- France
7
PUP -
Pôle Universitaire de Psychiatrie [CHU Bordeaux]
( 580918 )
- France
8
Service de Psychiatrie [CHRU Nancy]
( 223088 )
- 29 Avenue du Maréchal de Lattre de Tassigny 54000 Nancy
- France
9
Hôpitaux Sud -
Département Universitaire de Psychiatrie - [Hôpital Sainte Marguerite - APHM]
( 444127 )
- Hôpital Sainte-Marguerite
Bâtiment Solaris
270, boulevard de Sainte-Marguerite
13274 Marseille cedex 9
- France
10
Groupe Henri Mondor-Albert Chenevier
( 103061 )
- France
11
HUSLS-LRB-FW -
Département de Psychiatrie et de Médecine Addictologique [AP-HP HU Saint-Louis, Lariboisière, Fernand Widal]
( 557951 )
- France
12
Newcastle University [Newcastle]
( 252912 )
- Newcastle upon Tyne NE1 7RU
- Royaume-Uni
|
Langue du document |
Anglais
|
Nom de la revue |
|
Vulgarisation |
Non
|
Comité de lecture |
Oui
|
Audience |
Internationale
|
Date de publication |
2014-03
|
Volume |
157
|
Page/Identifiant |
8-13
|
Domaine(s) |
|
DOI | 10.1016/j.jad.2013.12.039 |
Pubmed Id | 24581821 |
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