The heart of the matter: years-saved from cardiovascular and cancer deaths in an elite athlete cohort with over a century of follow-up
Juliana Antero
(1)
,
Maja Pohar-Perme
(2)
,
Grégoire Rey
(3)
,
Jean-François Toussaint
(1, 4, 5)
,
Aurélien Latouche
(6)
1
IRMES - URP_7329 -
Institut de recherche biomédicale et d’épidémiologie du sport
2 UMCL - University Medical Centre Ljubljana [Ljubljana, Slovenia]
3 CépiDc - Centre d'épidémiologie sur les causes médicales de décès
4 UPD5 - Université Paris Descartes - Paris 5
5 CIMS - Centre d'Investigation en Médecine du sport
6 CEDRIC - MSDMA - CEDRIC. Méthodes statistiques de data-mining et apprentissage
2 UMCL - University Medical Centre Ljubljana [Ljubljana, Slovenia]
3 CépiDc - Centre d'épidémiologie sur les causes médicales de décès
4 UPD5 - Université Paris Descartes - Paris 5
5 CIMS - Centre d'Investigation en Médecine du sport
6 CEDRIC - MSDMA - CEDRIC. Méthodes statistiques de data-mining et apprentissage
Juliana Antero
- Fonction : Auteur
- PersonId : 741713
- IdHAL : juliana-antero
- ORCID : 0000-0001-6894-6693
Grégoire Rey
- Fonction : Auteur
- PersonId : 912678
Aurélien Latouche
- Fonction : Auteur
- PersonId : 760985
- ORCID : 0000-0001-9218-0333
Résumé
To quantify the years of life saved from cardiovascular (CVD), cancer and overall deaths among elite athletes according to their main type of physiological effort performed in the Olympic Games. All French athletes participating in the Games from 1912 to 2012, with vital status validated and cause of death (if concerned) identified by the national registries were included (n = 2814, 455 died) and classified according to 6 groups of effort: POWER (continuous effort < 45 s); INTERMEDIATE (45 s ≤ continuous effort < 600 s); ENDURANCE (continuous effort ≥ 600 s); POLYVALENT (participating in different events entering different classifications), INTERMITTENT (intermittent effort, i.e. team sports); PRECISION (targeting events). The theoretical years-lost method was adapted to calculate gains in longevity (years-saved) according to specific-risks under the competing risks model and was implemented in R software. Considering overall-deaths, all groups significantly saved, on average, 6.5 years of life (95% CI 5.8–7.2) compared to the general population. This longevity advantage is mainly driven by a lower risk of cancer which, isolated, contributed to significantly save 2.3 years of life (95% CI 1.2–1.9) on average in each group. The risk of CVD-related mortality in the ENDURANCE and PRECISION groups is not significantly different from the general population. The other groups significantly saved, on average, 1.6 years of life (95% CI 1.2–1.9) from CVD death. The longevity benefits in elite athletes are associated with the type of effort performed during their career, mainly due to differences on the CVD-risk of death.
Format du dépôt | Notice |
---|---|
Type de dépôt | Article dans une revue |
Titre |
en
The heart of the matter: years-saved from cardiovascular and cancer deaths in an elite athlete cohort with over a century of follow-up
|
Résumé |
en
To quantify the years of life saved from cardiovascular (CVD), cancer and overall deaths among elite athletes according to their main type of physiological effort performed in the Olympic Games. All French athletes participating in the Games from 1912 to 2012, with vital status validated and cause of death (if concerned) identified by the national registries were included (n = 2814, 455 died) and classified according to 6 groups of effort: POWER (continuous effort < 45 s); INTERMEDIATE (45 s ≤ continuous effort < 600 s); ENDURANCE (continuous effort ≥ 600 s); POLYVALENT (participating in different events entering different classifications), INTERMITTENT (intermittent effort, i.e. team sports); PRECISION (targeting events). The theoretical years-lost method was adapted to calculate gains in longevity (years-saved) according to specific-risks under the competing risks model and was implemented in R software. Considering overall-deaths, all groups significantly saved, on average, 6.5 years of life (95% CI 5.8–7.2) compared to the general population. This longevity advantage is mainly driven by a lower risk of cancer which, isolated, contributed to significantly save 2.3 years of life (95% CI 1.2–1.9) on average in each group. The risk of CVD-related mortality in the ENDURANCE and PRECISION groups is not significantly different from the general population. The other groups significantly saved, on average, 1.6 years of life (95% CI 1.2–1.9) from CVD death. The longevity benefits in elite athletes are associated with the type of effort performed during their career, mainly due to differences on the CVD-risk of death.
|
Auteur(s) |
Juliana Antero
1
, Maja Pohar-Perme
2
, Grégoire Rey
3
, Jean-François Toussaint
1, 4, 5
, Aurélien Latouche
6
1
IRMES - URP_7329 -
Institut de recherche biomédicale et d’épidémiologie du sport
( 1004825 )
- Institut National du Sport, de l’Expertise et de la Performance (INSEP)
11 avenue du Tremblay
75012 Paris
- France
2
UMCL -
University Medical Centre Ljubljana [Ljubljana, Slovenia]
( 562611 )
- Ljubljana
- Slovénie
3
CépiDc -
Centre d'épidémiologie sur les causes médicales de décès
( 172078 )
- 80 rue du Général Leclerc - Secteur Marron/Bâtiment LAFORCE/Porte 58 - 94270 Le Kremlin-Bicêtre Cedex
- France
4
UPD5 -
Université Paris Descartes - Paris 5
( 301664 )
- 12, rue de l'École de Médecine - 75270 Paris cedex 06
- France
5
CIMS -
Centre d'Investigation en Médecine du sport
( 223353 )
- 1 place du Parvis de Notre-Dame 75004 Paris
- France
6
CEDRIC - MSDMA -
CEDRIC. Méthodes statistiques de data-mining et apprentissage
( 390785 )
- France
|
Langue du document |
Anglais
|
Nom de la revue |
|
Vulgarisation |
Non
|
Comité de lecture |
Oui
|
Audience |
Internationale
|
Date de publication |
2018-06
|
Volume |
33
|
Numéro |
6
|
Page/Identifiant |
531-543
|
Domaine(s) |
|
DOI | 10.1007/s10654-018-0401-0 |
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