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Article Dans Une Revue American Journal of Human Biology Année : 2004

Duffy blood group genotyping in French Basques using polymerase chain reaction with allele-specific primers (PCR-ASP)

Résumé

Blood group antigens such as Duffy represent interesting models for population
genetics studies. The distribution of the Duffy blood group was determined using PCR in a sample of Basque (n ¼ 126) and non-Basque (n ¼ 110) patients fromthe general hospital of the French Basque Country. The frequency of FY*A allele was significantly lower among autochthonous French Basques (P <0.001). This result, obtained for the first time by PCR analysis in this population, was within the range of previous historical studies in various Basque subpopulations using traditional hemagglutination methods. When compared with European data, our Basque sample demonstrated the lowest FY*A/FY*B ratio, this fact confirming hemotypology data published before the molecular biology era. Our results with FY*X were quite similar to those reported in European populations.

Dates et versions

halshs-00008129 , version 1 (24-01-2006)

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Citer

Frédéric Bauduer, Mhammed Touinssi, Anna Degioanni, Stéphane Leroux, Olivier Dutour, et al.. Duffy blood group genotyping in French Basques using polymerase chain reaction with allele-specific primers (PCR-ASP). American Journal of Human Biology, 2004, 16 (1), pp.78-81. ⟨10.1002/ajhb.10230⟩. ⟨halshs-00008129⟩

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