Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice
Romane Cecchi
(1)
,
Fabien Vinckier
(2)
,
Jiri Hammer
(3)
,
Petr Marusic
(3)
,
Anca Nica
(4)
,
Sylvain Rheims
(5)
,
Agnès Trebuchon
(6, 7)
,
Emmanuel J. Barbeau
(8, 9)
,
Marie Denuelle
(8, 10)
,
Louis Maillard
(11)
,
Lorella Minotti
(12)
,
Philippe Kahane
(12)
,
Mathias Pessiglione
(11)
,
Julien Bastin
(1)
1
GIN -
[GIN] Grenoble Institut des Neurosciences
2 MBB - Equipe Motivation, cerveau et comportement = Motivation, Brain and Behavior [ICM Paris]
3 UPCité - Université Paris Cité
4 GHU Paris Psychiatrie et Neurosciences
5 UK - Univerzita Karlova [Praha, Česká republika] = Charles University [Prague, Czech Republic]
6 Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
7 TIMONE - Hôpital de la Timone [CHU - APHM]
8 CERCO UMR5549 - Centre de recherche cerveau et cognition
9 HCL - Hospices Civils de Lyon
10 CHU Toulouse - Centre Hospitalier Universitaire de Toulouse
11 CHRU Nancy - Centre Hospitalier Régional Universitaire de Nancy
12 CHUGA - Centre Hospitalier Universitaire [CHU Grenoble]
2 MBB - Equipe Motivation, cerveau et comportement = Motivation, Brain and Behavior [ICM Paris]
3 UPCité - Université Paris Cité
4 GHU Paris Psychiatrie et Neurosciences
5 UK - Univerzita Karlova [Praha, Česká republika] = Charles University [Prague, Czech Republic]
6 Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
7 TIMONE - Hôpital de la Timone [CHU - APHM]
8 CERCO UMR5549 - Centre de recherche cerveau et cognition
9 HCL - Hospices Civils de Lyon
10 CHU Toulouse - Centre Hospitalier Universitaire de Toulouse
11 CHRU Nancy - Centre Hospitalier Régional Universitaire de Nancy
12 CHUGA - Centre Hospitalier Universitaire [CHU Grenoble]
Romane Cecchi
- Fonction : Auteur
- PersonId : 815811
- ORCID : 0000-0002-6149-939X
Sylvain Rheims
- Fonction : Auteur
- PersonId : 761121
- ORCID : 0000-0002-4663-8515
- IdRef : 109032799
Agnès Trebuchon
- Fonction : Auteur
- PersonId : 807668
- ORCID : 0000-0002-8632-3454
- IdRef : 068710534
Emmanuel J. Barbeau
- Fonction : Auteur
- PersonId : 739693
- IdHAL : emmanuel-barbeau
- ORCID : 0000-0003-0836-3538
- IdRef : 080628990
Marie Denuelle
- Fonction : Auteur
- PersonId : 878806
- IdRef : 083381414
Julien Bastin
- Fonction : Auteur
- PersonId : 761638
- ORCID : 0000-0002-0533-7564
- IdRef : 113661304
Résumé
Identifying factors whose fluctuations are associated with choice inconsistency is a major issue for rational decision theory. Here, we investigated the neuro-computational mechanisms through which mood fluctuations may bias human choice behavior. Intracerebral EEG data were collected in a large group of subjects (n=30) while they were performing interleaved quiz and choice tasks that were designed to examine how a series of unrelated feedbacks affect decisions between safe and risky options. Neural baseline activity preceding choice onset was confronted first to mood level, estimated by a computational model integrating the feedbacks received in the quiz task, and then to the weighting of option attributes, in a computational model predicting risk attitude in the choice task. Results showed that (1) elevated broadband gamma activity (BGA) in the ventromedial prefrontal cortex (vmPFC) and dorsal anterior insula (daIns) was respectively signaling periods of high and low mood, (2) increased vmPFC and daIns BGA respectively promoted and tempered risk taking by overweighting gain vs. loss prospects. Thus, incidental feedbacks induce brain states that correspond to different moods and bias the evaluation of risky options. More generally, these findings might explain why people experiencing positive (or negative) outcome in some part of their life tend to expect success (or failure) in any other.
Format du dépôt | Fichier |
---|---|
Type de dépôt | Article dans une revue |
Résumé |
en
Identifying factors whose fluctuations are associated with choice inconsistency is a major issue for rational decision theory. Here, we investigated the neuro-computational mechanisms through which mood fluctuations may bias human choice behavior. Intracerebral EEG data were collected in a large group of subjects (n=30) while they were performing interleaved quiz and choice tasks that were designed to examine how a series of unrelated feedbacks affect decisions between safe and risky options. Neural baseline activity preceding choice onset was confronted first to mood level, estimated by a computational model integrating the feedbacks received in the quiz task, and then to the weighting of option attributes, in a computational model predicting risk attitude in the choice task. Results showed that (1) elevated broadband gamma activity (BGA) in the ventromedial prefrontal cortex (vmPFC) and dorsal anterior insula (daIns) was respectively signaling periods of high and low mood, (2) increased vmPFC and daIns BGA respectively promoted and tempered risk taking by overweighting gain vs. loss prospects. Thus, incidental feedbacks induce brain states that correspond to different moods and bias the evaluation of risky options. More generally, these findings might explain why people experiencing positive (or negative) outcome in some part of their life tend to expect success (or failure) in any other.
|
Titre |
en
Intracerebral mechanisms explaining the impact of incidental feedback on mood state and risky choice
|
Auteur(s) |
Romane Cecchi
1
, Fabien Vinckier
2
, Jiri Hammer
3
, Petr Marusic
3
, Anca Nica
4
, Sylvain Rheims
5
, Agnès Trebuchon
6, 7
, Emmanuel J. Barbeau
8, 9
, Marie Denuelle
8, 10
, Louis Maillard
11
, Lorella Minotti
12
, Philippe Kahane
12
, Mathias Pessiglione
11
, Julien Bastin
1
1
GIN -
[GIN] Grenoble Institut des Neurosciences
( 408885 )
- Site Santé - Bâtiment Edmond J. Safra - Chemin Fortuné Ferrini 38706 La Tronche Cedex
- France
2
MBB -
Equipe Motivation, cerveau et comportement = Motivation, Brain and Behavior [ICM Paris]
( 561457 )
- Institut du Cerveau,
Hôpital Pitié-Salpêtrière,
47 bd de l’Hôpital,
75013 Paris
- France
3
UPCité -
Université Paris Cité
( 557826 )
- 85 boulevard Saint-Germain
75006 Paris
- France
4
GHU Paris Psychiatrie et Neurosciences
( 559674 )
- 1 rue Cabanis 75674 Paris Cedex 14
- France
5
UK -
Univerzita Karlova [Praha, Česká republika] = Charles University [Prague, Czech Republic]
( 304738 )
- Ovocný trh 5
Prague 1
116 36
Czech Republic
- Tchéquie
6
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou]
( 301327 )
- 2 Rue Henri le Guilloux, 35000 Rennes
- France
7
TIMONE -
Hôpital de la Timone [CHU - APHM]
( 300093 )
- France
8
CERCO UMR5549 -
Centre de recherche cerveau et cognition
( 1149092 )
- CHU Purpan - Pavillon Baudot BP 25202 31052 Toulouse Cedex
- France
9
HCL -
Hospices Civils de Lyon
( 300074 )
- 3 Quai des Célestins
69002 Lyon
- France
10
CHU Toulouse -
Centre Hospitalier Universitaire de Toulouse
( 300075 )
- regroupe les hôpitaux Purpan, Rangueil, Pierre-Paul Riquet, Larey, Paule de Viguier, Hôtel Dieu Saint-Jacques, La Grave, etc.
- France
11
CHRU Nancy -
Centre Hospitalier Régional Universitaire de Nancy
( 300157 )
- Siège social : 29 avenue du Maréchal de Lattre de Tassigny, CO 60034, 54035 NANCY CEDEX
Hôpital Central : 29 Avenue du Maréchal de Lattre de Tassigny, 54035 Nancy
Hôpitaux de Brabois / Enfants : Rue du Morvan, 54500 Vandœuvre-lès-Nancy
Maternité régionale :10 Avenue Dr Heydenreich, 54000 Nancy
- France
12
CHUGA -
Centre Hospitalier Universitaire [CHU Grenoble]
( 257328 )
- CS 10217
38043 Grenoble cedex 9
- France
|
Page/Identifiant |
e72440
|
Nom de la revue |
|
Vulgarisation |
Non
|
Comité de lecture |
Oui
|
Audience |
Internationale
|
Date de publication |
2022-07-13
|
Volume |
11
|
Langue du document |
Anglais
|
Domaine(s) |
|
Projet(s) ANR |
|
DOI | 10.7554/eLife.72440 |
Pubmed Id | 35822700 |
PubMed Central | PMC9348847 |
Origine :
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