The development of transport infrastructures lead to increase the exposure of population to high noise levels. The objective of this work is to define an indicator representative of the health risk induced by noise pollution in urban environment and adapted to the geographical resolution of IRIS. The methodology for the definition of the indicator considers in a first part the health aspect with the health data for the following effects: annoyance, sleep disturbance and cardiovascular diseases. Then, in a second part, methodology considers some effects related to the urban context since the configuration of urban space can change the exposure of population to noise and the perception of noise. The work is achieved with a GIS software and the input acoustical data comes from noise maps calculated for the END. The indicator seems to be relevant and interesting as it brings health information.