Non-tariff measures (NTMs) play an increasing role in the international trade of agri-food products. Although well-recognized, this role has not been extensively analyzed at a disaggregated level. This paper focuses on NTMs enacted by member countries of the Organisation for Economic Co-operation and Development for 777 products. Using a cluster-analysis, the paper identifies the correlation between the occurrence of NTMs, their trade coverage, and the incidence of trade frictions for these products. The paper relates the statistical findings to the political economy literature on protection to explain cross-product differences in the occurrence of NTMs and trade frictions.