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Communication dans un congrès Année : 2017

Vaccine development and collaborations: lessons from the history of the meningococcal A vaccine

Résumé

In the early 1960s, following numerous warnings, the WHO decided to class meningitis as a public health priority in Africa. In light of its increasing resistance to sulfa-drugs, active immunization appeared to be the best approach to combatting this deadly disease, leading to new initiatives to produce an effective vaccine. This presentation will trace the history of the production of the meningococcal A vaccine, focusing on the collaborations engaged in the course of this project. The production of the vaccine involved the collaboration of several organisms under the aegis of the WHO: the Institut Mérieux in Lyon, the Centre International de Référence pour les Méningocoques du Pharo in Marseille, the Rockefeller Institute in New-York (specifically Dr. Emil C. Gotschlich), and many others in order to test the different versions of the vaccine. In this communication, we will cover a part of this history, considering the period from 1969 to 1973, and especially some key episodes which highlight the importance of this collaborative enterprise for the vaccine production. Indeed, a number of elements seemed to stand in the way of successfully producing a vaccine, and so the collaboration of the different actors under the aegis of the WHO provides some interesting lessons about how to manage this kind of project.
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Dates et versions

halshs-01632443, version 1 (10-11-2017)

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  • HAL Id : halshs-01632443 , version 1

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Baptiste Baylac-Paouly. Vaccine development and collaborations: lessons from the history of the meningococcal A vaccine. Annual Conference of HSTM Network of Ireland, in association with the RDS Library and Archives, Oct 2017, Dublin, Ireland. ⟨halshs-01632443⟩
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