Maternal genetic risk for depression and child human capital
Giorgia Menta
(1)
,
Anthony Lepinteur
(2)
,
Andrew E. Clark
(3, 4)
,
Simone Ghislandi
(5)
,
Conchita d'Ambrosio
(2)
Andrew E. Clark
- Fonction : Auteur
- PersonId : 742286
- IdHAL : andrew-clark
- ORCID : 0000-0001-7004-7654
- IdRef : 035800070
Résumé
We here address the causal relationship between the maternal genetic risk for depression and child human capital using UK birth-cohort data. We find that an increase of one standard deviation (SD) in the maternal polygenic risk score for depression reduces their children's cognitive and non-cognitive skill scores by 5 to 7% of a SD throughout adolescence. Our results are robust to a battery of sensitivity tests addressing, among others, concerns about pleiotropy and dynastic effects. Our Gelbach decomposition analysis suggests that the strongest mediator is genetic nurture (through maternal depression itself), with genetic inheritance playing only a marginal role.
Domaines
Economies et financesFormat du dépôt | Notice |
---|---|
Type de dépôt | Article dans une revue |
Titre |
en
Maternal genetic risk for depression and child human capital
|
Résumé |
en
We here address the causal relationship between the maternal genetic risk for depression and child human capital using UK birth-cohort data. We find that an increase of one standard deviation (SD) in the maternal polygenic risk score for depression reduces their children's cognitive and non-cognitive skill scores by 5 to 7% of a SD throughout adolescence. Our results are robust to a battery of sensitivity tests addressing, among others, concerns about pleiotropy and dynastic effects. Our Gelbach decomposition analysis suggests that the strongest mediator is genetic nurture (through maternal depression itself), with genetic inheritance playing only a marginal role.
|
Auteur(s) |
Giorgia Menta
1
, Anthony Lepinteur
2
, Andrew E. Clark
3, 4
, Simone Ghislandi
5
, Conchita d'Ambrosio
2
1
LISER -
Luxembourg Institute of Socio-Economic Research
( 462841 )
- 11, porte des Sciences 4366 Esch-sur-Alzette
- Luxembourg
2
University of Luxembourg [Luxembourg]
( 366875 )
- Campus Kirchberg
6, rue Richard Coudenhove-Kalergi
L-1359 Luxembourg
Campus de Limpertsberg
162a, avenue de la Faïencerie
L-1511 Luxembourg
Campus de Belval
2, avenue de l'Université
L-4365 Esch-sur-Alzette
- Luxembourg
3
PSE -
Paris School of Economics
( 301309 )
- 48 boulevard Jourdan 75014 Paris
- France
4
PJSE -
Paris Jourdan Sciences Economiques
( 578027 )
- 48 boulevard Jourdan 75014 Paris
- France
5
Bocconi University [Milan, Italy]
( 330935 )
- Via Sarfatti, 25 Milano
- Italie
|
Licence |
Paternité
|
Public visé |
Scientifique
|
Page/Identifiant |
102718
|
Vulgarisation |
Non
|
Comité de lecture |
Oui
|
Audience |
Internationale
|
Langue du document |
Anglais
|
Nom de la revue |
|
Date de publication |
2023-01
|
Volume |
87
|
Mots-clés (JEL) |
|
Domaine(s) |
|
Mots-clés |
en
Maternal depression, Human capital, ALSPAC
|
DOI | 10.1016/j.jhealeco.2022.102718 |
Pubmed Id | 36565586 |
UT key WOS | 000909917000001 |
Loading...