Ethics is a thick concept, in the way that it involves an irreducible hierarchy of values and significations, which are structured within a determined cultural background.Integrity is one of those key concepts within the field of ethics applied to research. As we all agree for freedom or justice, every scientist agree for integrity. But do we really know to what extent we are agreeing? If we can give negative definitions of those key concepts, nobody is able to explicit precisely their meaning neither to create consensus on their interpretation, as they imply different and incompatible worldviews. It opens a hermeneutic work and calls for discriminating intelligence of values, injunctions and interdictions involved in research. The cultural thickness of a country, of a language, of a scientific discipline or of a research establishment encompasses some intrinsic values which characterize the singularity of a complex symbolic structure.